Koshika

Human, exploring poetic technologies

Tag: Scientific Work

Natural Tr1-like cells do not confer long-term tolerogenic memory

Koshika Yadava # 1 2, Carlos Obed Medina # 1, Heather Ishak 1, Irina Gurevich 1, Hedwich Kuipers 1 3, Elya Ali Shamskhou 1, Ievgen O Koliesnik 1, James J Moon 4 5, Casey Weaver 6, Kari Christine Nadeau 7, Paul L Bollyky 1 PMID: 31603425 PMCID: PMC6788856 DOI: 10.7554/eLife.44821 Abstract IL-10-producing Tr1 cells promote tolerance but their contributions to tolerogenic memory are unclear. Using 10BiT mice that carry a Foxp3-eGFP reporter and stably express CD90.1 following IL-10 production, we characterized